April 10.2024

Corylin: A Natural Ingredient for a Younger You

Many people dream of staying young forever. Scientists and herbalists are working together to find new ways to fight aging, and Corylin is one exciting discovery!

What is Corylin?

Corylin is a natural substance found in an herb called Psoralea corylifolia, used in traditional Chinese medicine.



Corylin has been the subject of extensive research, with studies showing its potential to reduce obesity and insulin resistance, while promoting adipose tissue browning. The activation of SIRT-1 and β3-AR, two critical proteins in the body's metabolic pathways, is a key mechanism through which Corylin exerts its effects.


1. Reducing Obesity and Insulin Resistance

Scientists has demonstrated that Corylin can help in the fight against obesity by activating SIRT-1, a protein that regulates the body's metabolism and energy expenditure. By increasing the activity of this protein, Corylin aids in the breakdown of fat and the regulation of glucose levels, thus reducing insulin resistance, a common precursor to type 2 diabetes.


2. Promoting Adipose Tissue Browning

Adipose tissue browning refers to the transformation of white fat (which stores energy) into brown fat (which burns energy). This process is crucial for maintaining a healthy body weight and metabolic rate. Corylin has been shown to promote this browning process through the activation of β3-AR, leading to increased energy expenditure and a leaner body composition.



Lifespan Extension Properties

In addition to its metabolic benefits, Corylin has also been found to extend lifespan in mice. This groundbreaking discovery opens up new possibilities for the use of Corylin as an anti-aging supplement. The flavonoid's ability to enhance cellular health and resilience contributes to a longer, more vibrant life.


The Market for Anti-Aging Supplements

The anti-aging supplement market is vast and diverse, with consumers seeking natural and effective ways to maintain their health and slow down the aging process. From vitamins and minerals to plant-based compounds, there is a growing demand for products that can provide a competitive edge in the battle against aging.

Corylin stands out in this market due to its dual action of metabolic health and lifespan extension. Its natural origin and scientifically-backed benefits make it an attractive option for health-conscious consumers who are looking for a comprehensive solution to promote longevity and well-being.


Introducing Botanicure: Your Partner in Health and Longevity

Botanicure is a company at the forefront of the natural health movement. We specialize in the development and distribution of high-quality, science-backed supplements that cater to the needs of companies seeking to improve their products for health and longevity.


At Botanicure, we believe in the power of nature to provide solutions to modern health challenges. With Corylin, we offer a natural and effective way to support metabolic health and promote longevity. Join us in our mission to enhance lives through the wisdom of botanical cures.

The Future of Corylin:

While research on Corylin is promising, more studies are needed to see how it affects humans. We're following the research closely and look forward to learning more about Corylin's potential.

Corylin is a new discovery with big possibilities for staying healthy and living longer. At Botanicure, we're proud to be at the forefront of using Corylin in anti-aging solutions. Stay tuned as we explore the future of aging!


1. Wang TH, Tseng WC, Leu YL, Chen CY, Lee WC, Chi YC, Cheng SF, Lai CY, Kuo CH, Yang SL, Yang SH, Shen JJ, Feng CH, Wu CC, Hwang TL, Wang CJ, Wang SH, Chen CC. The flavonoid corylin exhibits lifespan extension properties in mouse. Nat Commun. 2022 Mar 9;13(1):1238. doi: 10.1038/s41467-022-28908-2. PMID: 35264584; PMCID: PMC8907184.

2. Chen, C.-C.; Li, H.-Y.; Leu, Y.-L.; Chen, Y.-J.; Wang, C.-J.; Wang, S.-H. Corylin Inhibits Vascular Cell Inflammation, Proliferation and Migration and Reduces Atherosclerosis in ApoE-Deficient Mice. Antioxidants 2020, 9, 275.

3. Chen CC, Kuo CH, Leu YL, Wang SH. Corylin reduces obesity and insulin resistance and promotes adipose tissue browning through SIRT-1 and β3-AR activation. Pharmacol Res. 2021 Feb;164:105291. doi: 10.1016/j.phrs.2020.105291. Epub 2020 Nov 27. PMID: 33253817.