April 03.2024

Isosinensetin: The Hidden Secret in the Pursuit of Health and Vitality



In today's quest for health and vitality, anti-aging has become a common concern. The market is flooded with various products claiming to slow down the aging process, yet often lacking scientific evidence and inconsistent in effectiveness. So, is there a more scientific and effective anti-aging solution?



The answer may lie in Isosinensetin, a newly discovered natural active ingredient from Bupleurum falcatum L. The latest research reveals that Isosinensetin can effectively promote the secretion of glucagon-like peptide-1 (GLP-1) by activating the hTAS2R50 receptor and the Gβγ-mediated signaling pathway in the human body. GLP-1 is a powerful intestinal hormone that not only helps regulate blood sugar levels but also promotes the release of insulin, providing energy for our bodies and maintaining a healthy weight.



As we age, our metabolism slows down, and levels of GLP-1 decrease accordingly. The unique action of Isosinensetin offers us an entirely new anti-aging strategy. By enhancing the secretion of GLP-1, Isosinensetin helps our bodies stay youthful and combat the challenges brought by aging.


Despite the wide variety of anti-aging health products on the market, many lack clear scientific support, making it difficult for consumers to judge their true effectiveness. Moreover, some products may contain unknown additives or ingredients, which could pose potential health risks with long-term use.


Against this market backdrop, Botanicure was born. We focus on researching and developing anti-aging products based on scientific evidence, committed to providing customers with safe and effective health solutions. Our goal is to fill the gap in the market and offer products that truly bring health benefits.


It is with this philosophy that we have introduced the cutting-edge active ingredient, Isosinensetin. Our research team works closely with international scientists to ensure that our products not only contain the highest quality ingredients but also undergo rigorous scientific validation.


We believe that the discovery of Isosinensetin is just the beginning of advancements in anti-aging science. As we investigate deeper into this field, we will continue to launch more innovative products to help people enjoy life in a healthier way.


On the journey of anti-aging, we invite you to join us. Choosing us means choosing a future that is younger and more vibrant. Let's welcome the new era of anti-aging together and uncover a new chapter of health and longevity.




[1] Lee SH, Ko HM, Jee W, Kim H, Chung WS, Jang HJ. Isosinensetin Stimulates Glucagon-like Peptide-1 Secretion via Activation of hTAS2R50 and the Gβγ-Mediated Signaling Pathway. Int J Mol Sci. 2023 Feb 12;24(4):3682. doi: 10.3390/ijms24043682. PMID: 36835092; PMCID: PMC9959872.


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